【Objective】

After Fukushima disaster in 2011, radioiodine fallout could be largely incorporated and fixed in the xyloglucan of cell walls in Fukushima forest trees. Since xyloglucan has been used for the food glycan, we attempted to use xyloglucan instead of the stable iodine tablets for human bodies against radioiodine. At first, we examined the levels of non-digested xyloglucan through human bodies and also the effects of xyloglucan on the bodies.

【Method】

Three healthy subjects were given 10g x 7days of xyloglucan, and their excretion in the stool was examined. Ten healthy subjects their 20s who were subjected to a normal initial triglyceride level range of 60-150 mg/dl were selected and subjected to 10 g of xyloglucan per day for 7 days to examine changes in blood parameters between before and after intake of xyloglucan was determined by t-test.

【Result】

In three healthy subjects of xyloglucan was metabolized and remained 4.1% in the stool. The change in mean stool volume due to xyloglucan ingestion increased from 128 g/day before ingestion to 161 g/day after ingestion period.

In ten healthy subjects xyloglucan ingestion significantly reduced significantly (p<0.05) both blood cholesterol levels from 175.4 mg/dl to 166.7 mg/dl and triglycerides from 98.8 mg/dl to 73.4 mg/dl, respectively.

This is the first report on the effect of improving lipid metabolism in continuous intake of xyloglucan in humans. In this study, the presence of xyloglucan in feces was small, suggesting the effect of assimilation by intestinal bacteria and the effect of short chain fatty acids, which are assimilation products, on lipid metabolism.

1)Nonaka, M. et.al Forests, 11, 957,1-10(2020); doi:10.3390/f11090957 www.mdpi.com/journal/forests

2)Yamatoya, K. et. al, In Hydrocolloids Part 2,p.405-410.(2000